Is this Diacerein 50mg + Glucosamine 1500mg Tablet effective for severe knee joint swelling and pain?

This combination is commonly used for osteoarthritis-related joint pain diacerein works gradually to reduce the inflammatory processes behind cartilage damage, while glucosamine supports joint cartilage over time. It's worth knowing that diacerein takes a few weeks to show its full effect and can cause loose stools in some people when starting out, so it isn't a quick fix for a sudden flare. Given you're describing it as severe, please have a doctor examine the knee itself, since more urgent swelling sometimes needs additional treatment alongside this tablet.