Avas 20mg Tablet 30s

Avas 20mg Tablet 30s is a cholesterol-lowering drug belonging to the statin class. It is primarily used for the treatment of hyperlipidemia (high cholesterol) and for reducing the risk of cardiovascular events in patients with heart disease. Avas 20mg Tablet 30s works systemically by inhibiting an enzyme in the liver, lowering LDL cholesterol levels, and preventing plaque buildup in arteries. This formulation often refers to a single, standard tablet designed for convenient, daily dosing.

Avas 20mg Tablet 30s is the generic name for a statin-class medication that inhibits HMG-CoA reductase. Its efficacy in treating hyperlipidemia and preventing cardiovascular disease is attributed to its systemic action in reducing cholesterol synthesis in the liver. The oral dosage is typically part of a daily regimen, often required to be taken once daily, utilising its lipophilic properties to ensure effective absorption and distribution throughout the body, where cholesterol management is most needed.

Long-term treatment for high cholesterol relies on the maintenance of lipid levels, and Avas 20mg Tablet 30s is the cornerstone medication for this purpose in patients with increased LDL cholesterol or at cardiovascular risk.

By lowering LDL cholesterol and triglycerides while raising HDL, Avas 20mg Tablet 30s helps reduce plaque buildup in arteries, alleviates risks like heart attacks and strokes, and reduces the risk of long-term complications, including atherosclerosis progression associated with chronic hyperlipidemia. Due to the chronic nature of high cholesterol, patients often remain on maintenance therapy with Avas 20mg Tablet 30s for years.

Avas 20mg Tablet 30s is indicated for:

• Treatment of High Cholesterol (Hyperlipidemia): Used to lower elevated LDL cholesterol and total cholesterol levels in patients with primary hyperlipidemia.
• Reduction of Cardiovascular Risk in Heart Disease: Helps prevent heart attacks, strokes, and other events in patients with existing coronary artery disease or multiple risk factors.
• Primary Prevention in High-Risk Patients: Indicated for individuals without clinical heart disease but with diabetes, hypertension, or other risks to reduce the chance of first cardiovascular events.
• Management of Mixed Dyslipidemia: Effective in lowering triglycerides while increasing HDL cholesterol for better overall lipid control.

• Proven Cholesterol Reduction: Strongly lowers "bad" LDL cholesterol by up to 60% and triglycerides, directly addressing the root cause of plaque buildup in arteries.
• Cardiovascular Protection: Reduces the risk of major events like heart attacks and strokes by 25-40% in high-risk patients, supporting long-term heart health.
• Convenient Once-Daily Use: Simple regimen improves adherence, making it easier to maintain consistent cholesterol control over time.
• Favourable Safety Profile: Well-tolerated for lifelong use with fewer side effects than alternatives, suitable even for patients needing extended therapy.
• Improved Quality of Life: By preventing complications, it helps patients avoid hospitalisations and live more active lives free from cardiovascular worries.

When taken as directed, Avas 20mg Tablet 30s is generally safe. Side effects are usually rare, mild, and temporary.

Common Side Effects (Mild and temporary):

• Muscle pain or weakness
• Headache
• Stomach upset or diarrhoea
• Nausea
• Sleep disturbances

Serious Side Effects (Stop taking the medicine and seek urgent medical attention if you experience):

• Severe muscle damage (Rhabdomyolysis): Unexplained muscle pain, tenderness, weakness, dark urine, or fever.
• Serious Allergic Reaction (Anaphylaxis): Rash, itching, swelling of the face, throat, or tongue, severe dizziness, or trouble breathing.
• Signs of Liver Damage: Yellowing of the skin or eyes (jaundice), dark urine, severe fatigue, or upper right abdominal pain.
• Memory problems or confusion (Rare): Sudden forgetfulness, disorientation, or mental changes.

• Dosage: The total daily dosage varies based on cholesterol levels and cardiovascular risk (typically 10mg to 80mg daily). Doses are usually taken once daily in the evening when cholesterol production is highest.
• Administration: Swallow the tablet whole with water. Take with or without food, but avoid grapefruit juice as it can increase side effect risks. Consistency in timing helps maintain steady blood levels.
• Consistency: Take Avas 20mg Tablet 30s exactly as directed, even if feeling well, to maintain cholesterol control and prevent cardiovascular events. Regular blood tests monitor effectiveness and safety.

• Long-Term Use: Even if cholesterol levels improve and you feel well, continue taking Avas 20mg Tablet 30s exactly as prescribed. Stopping prematurely allows cholesterol to rebound, increasing heart attack and stroke risks.
• Liver Monitoring: Regular liver function tests (LFTs) are essential, especially in the first few months, to catch any rare elevation early.
• Watch for Muscle Pain: Report unexplained muscle aches, weakness, dark urine, or fever immediately, as these could signal serious muscle damage (rhabdomyolysis).
• Avoid Grapefruit: Never consume grapefruit juice or products, as they dangerously increase drug levels and side effect risks.
• Diet and Exercise: Combine Avas 20mg Tablet 30s with a low-cholesterol diet and regular physical activity for maximum heart protection benefits.

Store at room temperature (typically below 25°C or 77°F).

Keep the container tightly closed and protect the tablets from moisture and light.

Keep out of reach of children.

• General: Food does not significantly affect the absorption of Avas 20mg Tablet 30s, so it can generally be taken with or without meals for consistent results.
• Diet: While no direct food interactions exist, following a heart-healthy diet low in saturated fats and cholesterol enhances the medication's cholesterol-lowering effects and supports overall cardiovascular health.

• Fibrates (Gemfibrozil, Fenofibrate): Significantly increase the risk of muscle damage (rhabdomyolysis); use with extreme caution or avoid.
• Cyclosporine or HIV Protease Inhibitors: Greatly increases Avas 20mg Tablet 30s blood levels, requiring substantial dose reduction.
• Warfarin (Blood Thinner): May enhance anticoagulant effects; requires close INR monitoring.
• Antacids (Calcium/Magnesium/Aluminium-containing): Reduce absorption; separate by at least 2 hours.
• Clarithromycin or Other Strong CYP3A4 Inhibitors: Increases side effect risk; dose adjustment needed.

• Renal Impairment (Kidney Disease): Increased risk of muscle-related side effects; dose adjustment required in moderate to severe cases.
• Hepatic Impairment (Liver Disease): Contraindicated in active liver disease; requires careful monitoring and possible dose reduction.
• Hypothyroidism: May increase risk of muscle damage; thyroid levels should be optimised before starting therapy.
• Muscle Disorders (Myopathy): Higher risk of rhabdomyolysis in patients with a history of muscle problems.

For cholesterol management, the daily dose typically ranges from 10mg to 80mg (one tablet). Lower doses suit most patients; higher doses are for those needing a greater reduction. Always follow your doctor's specific prescription.

An overdose can cause severe muscle breakdown, liver damage, or kidney failure. Symptoms include extreme muscle pain, weakness, dark urine, nausea, vomiting, or yellowing skin. Action Required: Seek immediate emergency medical attention. Treatment involves stopping the drug, IV fluids, and monitoring organ function.

If you miss a dose of Avas 20mg Tablet 30s, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.