I have a prescription for Divalproex Sodium sustained-release tablets 250mg for bipolar affective disorder. Can I switch to a different manufacturer's version of the same tablet?

Tablets that contain the same salt, Divalproex Sodium, at the same 250mg sustained-release strength are generally considered therapeutically equivalent, whichever manufacturer makes them. For a condition like BPAD though, consistency matters, and mood-stabilizer levels can occasionally behave a little differently between brands in sensitive individuals. It's worth showing your psychiatrist or pharmacist the new pack before you switch, just to be safe.