Substitute of Cofdex Tablet
Salt Composition
Caffeine 30mg + Diphenhydramine 25mg + Paracetamol (Acetaminophen) 500mg + Phenylephrine 5mg
Primary Use
Caffeine, Diphenhydramine, Paracetamol, and Phenylephrine are used in the treatment of the common cold.
Original Brand
Cipla Ltd.
Standard Price
Syed Jommy Abbas, Pharmacist
B. Pharma
Devika Rani, MBBS
MBBS
Looking for an affordable alternative to Cofdex Tablet? The substitutes below contain the exact same active ingredients Caffeine + Diphenhydramine + Paracetamol (Acetaminophen) + Phenylephrine and offer identical therapeutic benefits.
Top Substitutes by Savings
All alternatives listed below contain the exact same active ingredients and are approved for the same medical uses as Cofdex Tablet.
Medicine NAME
PRICE
Cetzine Cold Tablet 10s
Dr. Reddy's Laboratories Ltd.
MRP: ₹44.8 (10 Tablets)
₹4.5/unit
26% Lower Price
26% Lower Price
View DetailsNicip Cold & Flu 30mg Tablet 10s
Cipla Ltd.
MRP: ₹72.4 (10 Tablets)
₹7.2/unit
35% Lower Price
35% Lower Price
View DetailsNoblok New Tablet 10s
Mankind Pharmaceuticals Ltd.
MRP: ₹49.7 (10 Tablets)
₹5/unit
18% Lower Price
18% Lower Price
View DetailsKlavease Cold Tablet 10s
Johnlee Pharmaceuticals Pvt. Ltd.
MRP: ₹84.4 (10 Tablets)
₹8.4/unit
31% Lower Price
31% Lower Price
View DetailsCC NEED JUMBO Tablet
Dr. Morepen Ltd.
MRP: ₹67.5 (10 Tablets)
₹6.8/unit
28% Lower Price
28% Lower Price
View DetailsNew Hatric 3 Tablet
Aristo Pharmaceuticals Pvt. Ltd.
MRP: ₹54.4 (10 Tablets)
₹5.4/unit
11% Lower Price
11% Lower Price
View DetailsSumo Cold 30/25/500/5mg Tablet 10s
Alkem Laboratories Ltd.
MRP: ₹55.7 (10 Tablets)
₹5.6/unit
9% Lower Price
9% Lower Price
View DetailsSudin Cold Tablet 10s
Group Pharmaceuticals Ltd.
MRP: ₹64.7 (10 Tablets)
₹6.5/unit
Cost 6% more
Cost 6% more
View DetailsVicks Action Advanced Tablet 10s
Procter & Gamble Hygiene & Healthcare Ltd.
MRP: ₹64 (10 Tablets)
₹6.4/unit
Cost 5% more
Cost 5% more
View DetailsAllerhin Cold Tablet 10s
Embiotic Laboratories Pvt. Ltd.
MRP: ₹67.5 (10 Tablets)
₹6.8/unit
Cost 11% more
Cost 11% more
View DetailsColdofer Tablet 10s
Pristine Organics Pvt. Ltd.
MRP: ₹70.3 (10 Tablets)
₹7/unit
Cost 15% more
Cost 15% more
View DetailsMaxtra Cold Plus Tablet 10s
Zuventus Healthcare Ltd.
MRP: ₹73.8 (10 Tablets)
₹7.4/unit
Cost 21% more
Cost 21% more
View DetailsNuhist Tablet 10s
NuLife Pharmaceuticals
MRP: ₹93.8 (10 Tablets)
₹9.4/unit
Cost 54% more
Cost 54% more
View DetailsWincit D Tablet 10s
Syswin Pharmaceuticals Pvt. Ltd.
MRP: ₹210.9 (10 Tablets)
₹21.1/unit
Cost 246% more
Cost 246% more
View DetailsUses
Caffeine, Diphenhydramine, Paracetamol, and Phenylephrine are used in the treatment of the common cold.
Side Effects
Common side effects of caffeine, diphenhydramine, paracetamol, and phenylephrine include nausea, vomiting, insomnia (difficulty sleeping), dizziness, impaired coordination, headache, sedation, inability to concentrate, irritability, tremors, diarrhea, dry mouth, fatigue, and blurred vision.
How it Works
How Caffeine, Diphenhydramine, Paracetamol, and Phenylephrine Work Caffeine, Diphenhydramine, Paracetamol, and Phenylephrine is a combination of four medications that alleviates common cold symptoms.
Safety Advice
Breastfeeding
Safe
Generally safe for topical use, but do not apply to the breast area to prevent the infant from ingesting the medicine.
Driving
Safe
Topical use does not affect your ability to drive.
Liver
Safe
Minimal systemic absorption means it is generally safe for those with liver issues.
Kidney
Safe
Generally safe, though avoid large-scale application if you have severe kidney disease.
Alcohol
Safe
No known interactions with alcohol for topical use.
Pregnancy
Unsafe
This should be used only if the potential benefit justifies the potential risk to the fetus.
Breastfeeding
Safe
Generally safe for topical use, but do not apply to the breast area to prevent the infant from ingesting the medicine.
Driving
Safe
Topical use does not affect your ability to drive.
Liver
Safe
Minimal systemic absorption means it is generally safe for those with liver issues.
Kidney
Safe
Generally safe, though avoid large-scale application if you have severe kidney disease.
Alcohol
Safe
No known interactions with alcohol for topical use.
Pregnancy
Unsafe
This should be used only if the potential benefit justifies the potential risk to the fetus.
Is it Safe to Switch?
The Same Salt and Strenght Rule
The core of any medication is its active ingredient, or "salt." Whether you buy the original Cofdex Tablet or a substitute, the active ingredient Caffeine + Diphenhydramine + Paracetamol (Acetaminophen) + Phenylephrine is exactly the same. By law, generics must be bioequivalent, delivering the exact same dosage into your bloodstream at the same rate. Therapeutically, your body cannot tell the difference.
When not to switch
While the active salt is identical, inactive ingredients (binding agents, colors) vary. Consult your doctor if:
Specific Allergies:You are sensitive to certain dyes or lactose fillers.
Release Mechanisms:You are unsure if the new pill matches your prescribed release profile (IR/ER/SR).
Crucial Steps Before Changing
Verify the Strength & Release Profile
Double-check your prescription for two critical details before switching brands:
Release Speed:Pills dissolve at different rates. Check the letters on your prescription. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Exact Strength:The milligrams must match perfectly. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Consult Your Physician
Your doctor knows your complete medical history. Don't wait weeks for an appointment just to switch brands. Consult a verified doctor online through PlatinumRx in minutes.
Myths vs. Facts About Generic Medicines
Don't let misinformation stop you from saving money. Here is the truth about generic medications.
Cheaper medicines are lower quality and take longer to work.
Generics act in the body at the exact same speed. They cost less because they do not pay for initial R&D and heavy TV marketing.
Generic drugs cause more side effects or stomach issues.
The active medicinal ingredients are 100% identical. Regulatory bodies ensure the generic's safety profile matches the original.
Generic companies skip safety testing to save money.
False. Manufacturers must pass rigorous bioequivalence testing to prove their pill behaves like the original in the human body.