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Isotretinoin

Uses

Isotretinoin is used in the treatment of acne.

How it Works

Isotretinoin is a derivative of vitamin A. It acts on the sebaceous glands to reduce the production of sebum, a natural substance that contributes to acne. Additionally, controlled sebum production helps eliminate acne-causing bacteria. Isotretinoin also functions as an anti-inflammatory agent, decreasing inflammation, redness, and swelling.

Side Effects

Common side effects of Isotretinoin include dry skin, dry eyes, dermatitis, dry lips, nosebleeds, back pain, joint pain, headache, nasopharyngitis (inflammation of the throat and nasal passages), increased creatine phosphokinase levels in the blood, lip inflammation, and reduced visual acuity.

Expert Advice

You have been prescribed Isotretinoin for the treatment of severe acne.
Take it with food.
Avoid exposure to sunlight while using Isotretinoin.
Use protective measures such as sunscreen or protective clothing.
Avoid face waxing and laser treatments while using this medication, as it may make your skin more fragile.
Avoid taking tetracycline, as it may reduce the effectiveness of Isotretinoin.
Do not take Isotretinoin if you are pregnant, planning to become pregnant, or breastfeeding.
It may cause dryness of the mouth, lips, and eyes.
Drink plenty of water, use moisturizer, and avoid wearing contact lenses.
Inform your doctor if you experience any bothersome symptoms.

Other Combinations

Clindamycin + Isotretinoin

Related Medications

Salt Composition in both

Isotretinoin 20mg

Sotret 20mg Capsule 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 capsules

₹330.9

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

Strip of 10 capsules

₹166.3

MRP ₹332.5

Salt Composition in both

Isotretinoin 20mg

Isotroin 20mg Capsule 15s

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₹519.6

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

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₹166.3

MRP ₹332.5

Salt Composition in both

Isotretinoin 20mg

Acnex 20mg Capsule 10s

Torrent Pharmaceuticals Ltd.

Strip of 10 capsules

₹159.5

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

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₹166.3

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Salt Composition in both

Isotretinoin 20mg

Acne Rob 20mg Capsule 10s

Park Pharmaceuticals

Strip of 10 capsules

₹150

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

Strip of 10 capsules

₹166.3

MRP ₹332.5

Salt Composition in both

Isotretinoin 20mg

Wellnoin 20mg Soft Gelatin Capsule

Spairowell Dermacare

Strip of 10 capsules

₹179

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

Strip of 10 capsules

₹166.3

MRP ₹332.5

Salt Composition in both

Isotretinoin 20mg

Akmiret Soft Gelatin Capsule

Strip of 10 capsules

₹195

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

Strip of 10 capsules

₹166.3

MRP ₹332.5

Salt Composition in both

Isotretinoin 20mg

Isotrex 20mg Capsule

Asoj Soft Caps Pvt. Ltd.

Strip of 10 capsules

₹150

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

Strip of 10 capsules

₹166.3

MRP ₹332.5

Salt Composition in both

Isotretinoin 20mg

Isonon 20mg Soft Gelatin Capsule

Senechio Pharma Pvt. Ltd.

Strip of 10 capsules

₹165

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

Strip of 10 capsules

₹166.3

MRP ₹332.5

Salt Composition in both

Isotretinoin 20mg

Gebitret 20mg Soft Gelatin Capsule

Oddiant Formulations

Strip of 10 capsules

₹185

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

Strip of 10 capsules

₹166.3

MRP ₹332.5

Salt Composition in both

Isotretinoin 20mg

Xtrion 20mg Capsule

Trans Life Sciences

Strip of 10 capsules

₹170

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

Strip of 10 capsules

₹166.3

MRP ₹332.5

Salt Composition

Isotretinoin 20mg

Skin Fine ISO 20mg Capsule 10s

Dr. Morepen Ltd.

Strip of 10 capsules

₹166.3

MRP ₹332.5

Salt Composition

Isotretinoin 30mg

Accufine 30mg Capsule 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 capsules

₹180.5

MRP ₹360.9

Salt Composition in both

Isotretinoin 10mg

Trato 10mg Soft Gelatin Capsule

Eclipser Pharmaceuticals

Strip of 10 capsules

₹80

Acnetoin I 10mg Capsule 10s

Leeford Healthcare Ltd.

Strip of 10 capsules

₹63.3

MRP ₹126.5

Salt Composition

Isotretinoin 5mg

Glotret 5mg Tablet 10s

Glowderma Labs Pvt. Ltd.

Strip of 10 tablets

₹87.6

MRP ₹106.9

Salt Composition in both

Isotretinoin 10mg

Glotret 10mg Tablet 10s

Glowderma Labs Pvt. Ltd.

Strip of 10 tablets

₹168.8

Xotroin 10mg Tablet 10s

Supraceuticals Pvt. Ltd.

Strip of 10 tablets

₹112.8

MRP ₹135.9

Salt Composition in both

Isotretinoin 20mg

Tinytret 20mg Tablet 10s

Amwill Healthcare

Strip of 10 tablets

₹234.4

Isohex 20mg Capsule 10s

Hexadox Pharmaceuticals Pvt. Ltd.

Strip of 10 capsules

₹202.3

MRP ₹243.8

Salt Composition

Isotretinoin 20mg

Isohex 20mg Capsule 10s

Hexadox Pharmaceuticals Pvt. Ltd.

Strip of 10 capsules

₹202.3

MRP ₹243.8

Salt Composition in both

Isotretinoin 20mg

Isoquibb Tablet

Strip of 10 tablets

₹149

Isohex 20mg Capsule 10s

Hexadox Pharmaceuticals Pvt. Ltd.

Strip of 10 capsules

₹202.3

MRP ₹243.8

Salt Composition in both

Isotretinoin 10mg

Zipac 10mg Tablet

Maxamus Pharma Pvt. Ltd.

Strip of 10 tablets

₹90

Xotroin 10mg Tablet 10s

Supraceuticals Pvt. Ltd.

Strip of 10 tablets

₹112.8

MRP ₹135.9

Salt Composition

Isotretinoin

Acno Cream 15gm

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₹45

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Isotretinoin

Acno(Intas) Soap

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Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Isotretinoin

Airet HC Lotion 10ml

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Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Isotretinoin

Airet HC Cream 15gm

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Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Isotretinoin 0.025%

A Ret 0.025% Gel 20gm Shalaks Healthcare

Shalaks Healthcare

₹120

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Isotretinoin 25mg

Tretiva 25 Capsule

Intas Pharmaceuticals Ltd.

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₹285

Sorry, the substitute medicine is Currently Unavailable

Frequently asked questions

Is Isotretinoin a steroid?

No, Isotretinoin is a retinoid (vitamin A) used to treat severe acne.

Is Isotretinoin safe to use?

Isotretinoin should be used cautiously due to potential significant adverse reactions. It is intended for patients with severe nodular acne unresponsive to conventional treatments, including systemic antibiotics. Pregnant women must avoid it due to the risk of severe birth defects.

Can Isotretinoin cause cancer?

No, Isotretinoin has not been linked to cancer; it may even be beneficial for certain head, skin, and neck cancers.

Does Isotretinoin damage your liver?

Isotretinoin may cause a transient increase in liver enzymes, necessitating regular monitoring. These levels typically normalize over time, but persistent elevation may lead to discontinuation of the medication.

Does Isotretinoin affect male fertility?

No, Isotretinoin does not impact male fertility, with no significant changes observed in ejaculate volume, sperm count, motility, morphology, or seminal plasma fructose.

Is the effect of Isotretinoin permanent?

Many patients experience lasting improvement after a single 15-20 week course. If a second course is needed, it should be initiated at least 8 weeks after the first, as symptoms may continue to improve post-treatment.

Why is Isotretinoin so dangerous during pregnancy?

Isotretinoin poses a high risk of severe birth defects if pregnancy occurs during treatment.

What are the long-term side effects of Isotretinoin?

Long-term effects of low doses have not been extensively studied, but Isotretinoin may affect bone mineral density, potentially leading to osteoporosis or fractures.

What are the recommended tests during Isotretinoin therapy?

Liver enzymes and serum lipid levels are checked before treatment and monitored one month after starting, then every three months unless more frequent testing is clinically indicated.

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