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Azathioprine

Uses

Azathioprine is used in the prevention of organ rejection in transplant patients and in the treatment of rheumatoid arthritis.

How it Works

How Azathioprine Works Azathioprine is an immunosuppressant that reduces the activity of the body's immune system and helps prevent the rejection of transplanted organs. Additionally, it inhibits the action of specific chemical messengers responsible for inflammation, swelling, and redness associated with certain joint diseases.

Side Effects

Common side effects of Azathioprine include nausea, infection, low blood platelets, vomiting, and bone marrow suppression.

Expert Advice

  • Your doctor has prescribed Azathioprine to prevent the body from rejecting a transplanted organ (e.g., kidney, heart, or liver).
  • Azathioprine also alleviates joint pain and inflammation associated with rheumatoid arthritis.
  • You may need to take additional medications alongside Azathioprine for improved symptom relief.
  • Avoid contact with individuals who have a cold, flu, or other contagious illnesses.
  • Notify your doctor if you experience any signs of infection, such as fever or sore throat.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

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Frequently asked questions

Yes, Azathioprine may increase the risk of certain cancers, including skin cancer, lymphoma, sarcomas, and cervical cancer. To mitigate skin cancer risk, avoid prolonged sun exposure and use protective measures. Report any skin changes or lumps to your doctor immediately.
Yes, Azathioprine and cyclosporine can be taken together as they do not interfere with each other. Follow your doctor's instructions for both medications.
The duration of Azathioprine treatment varies based on individual medical conditions and should be determined by your doctor.
No, breastfeeding should be avoided during Azathioprine treatment due to potential harm and serious side effects for the baby.
If you miss a dose, take it as soon as you remember. If it's close to your next dose, skip the missed dose. Do not double up on doses, and inform your doctor if you frequently miss doses.
Yes, regular blood tests are necessary to monitor blood cell production and liver function due to Azathioprine's effects. Initially, weekly blood tests may be required for the first 8 weeks, followed by monthly or quarterly tests.
Azathioprine may take 3 to 12 weeks to show benefits. Continue taking the medication even if you don't notice immediate effects, and consult your doctor if you have concerns.
Azathioprine is an immunosuppressant that suppresses the immune system to treat conditions caused by its overactivity. It prevents organ transplant rejection and treats chronic active hepatitis, severe rheumatoid arthritis, systemic lupus erythematosus, idiopathic thrombocytopenic purpura, acquired hemolytic anemia, and severe skin diseases when corticosteroids are unsuitable.
Long-term use of Azathioprine may increase the risk of severe infections, decreased blood cell counts, and malignancy. Notify your doctor if you experience infections, fever, unusual bruising or bleeding, black tarry stools, blood in urine or stools, or any new skin sores or changes in existing skin marks.
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